Authors: Sanne van der Mark, Peter Klaver, Kerstin Bucher, Urs Maurer, Enrico Schulz, Silvia Brem, Ernst Martin, Daniel Brandeis.
Article: The left occipitotemporal system in reading: Disruption of focal fMRI connectivity to left inferior frontal and inferior parietal language areas in children with dyslexia.
Publication: NeuroImage (Elsevier). Volume 54, Issue 3, Pages 2426-2436 2011 | DOI: 10.1016/j.neuroimage.2010.10.002
► Mainly the VWFA was functionally connected with typical left frontal and parietal language areas in control children, pointing to a focal origin of connectivity from the VWF-System. ► Children with dyslexia showed significant disruption of functional connectivity between the VWFA and left inferior frontal and left inferior parietal language areas. ► A functional disconnection of the left occipitotemporal system in children with dyslexia is limited to the small VWFA region crucial for automatic visual word processing ► This functional disconnection may be linked to dyslexics’ deficits in phonological processing since connectivity was correlated with phonological performance in the control group but not in the children with dyslexia. ► This functional disconnection emerges early during reading acquisition in children with dyslexia, along with deficits in orthographic and phonological processing of visual word forms.